Contents
What Is PDRN?
2025 Korean Beauty Guide: How to Use PDRN Ampoule for Glowing, Rejuvenated Skin๏ผBefore learning how to use it, letโs understand whatย PDRN (Polydeoxyribonucleotide)ย actually is.
PDRN is a DNA-based regenerative ingredient extracted from salmon.
Itโs widely used in Korean dermatology clinics and โRejuran Healerโ injections โ
and now, itโs available in skincare ampoules you can easily use at home.
Key benefits:
- Boosts skin regeneration and repair
- Improves elasticity and firmness
- Brightens dull and uneven skin tone
- Soothes sensitive or irritated skin
Think of PDRN as a โskin healerโ that helps your skin repair itself from within.

Why PDRN Ampoules Are Trending in K-Beauty
Korean consumers (and now global beauty lovers) love PDRN ampoules because they provide medical-grade resultsin a daily skincare format.
Unlike basic serums, PDRN ampoules:
- Penetrate deep into the dermis
- Stimulate collagen and DNA repair
- Deliver visible improvement in skin texture within 2โ4 weeks
Youโll find top brands like CNP Laboratory, Medicube, and Anua offering PDRN ampoules at Olive Young โ Koreaโs most popular beauty retailer.
Step-by-Step: How to Use PDRN Ampoule
๐ Morning Routine
- Cleanse โ Wash your face with a mild cleanser.
- Tone โ Use a hydrating toner to prep your skin.
- Apply PDRN Ampoule โ Take 2โ3 drops and gently pat onto your face. Focus on dull or damaged areas.
- Moisturize โ Seal in the ampoule with a light moisturizer.
- Sunscreen โ Always finish with SPF during the day.
โ Tip: PDRN ampoules layer well under makeup โ they create a smooth, dewy base.
๐ Night Routine
- Double Cleanse โ Remove makeup and cleanse thoroughly.
- Apply PDRN Ampoule โ Use a slightly larger amount (4โ5 drops).
- Massage Gently โ Tap with fingertips until fully absorbed.
- Follow with a Cream โ Use a nourishing or peptide-based cream for overnight repair.
๐ Tip: For intensive care, mix 1โ2 drops of ampoule into your sleeping pack or sheet mask essence.
How Often Should You Use It?
- For normal skin โ Once a day (morning or night)
- For dry or sensitive skin โ Twice a day
- For post-procedure care (laser, peeling, etc.) โ Consult your dermatologist, but itโs often safe to apply 2ร daily
Visible results can appear after 2 weeks of continuous use:
- Brighter complexion
- Reduced fine lines
- Smoother, firmer texture

Recommended PDRN Ampoules (Available at Olive Young)
| Brand | Product | Highlights |
|---|---|---|
| CNP Laboratory | Derma+ Answer PDRN Ampoule | Deep pore care, elasticity boost, hypoallergenic |
| Medicube | PDRN Pink Peptide Ampoule | Brightening + firming dual care |
| Anua | PDRN Hyaluronic Capsule 100 Serum | Instant hydration + collagen activation |

Pro Tips to Maximize the Effect
- Store in a cool, dark place to protect the DNA ingredient.
- Avoid using directly after acids (AHA/BHA) โ apply PDRN afterward to soothe skin.
- Combine with a vitamin C serum in the morning for a brightening boost.
- Donโt skip sunscreen! Regenerating skin is more sensitive to UV rays.
Final Thoughts
PDRN ampoules are one of Koreaโs most advanced skincare innovations โ
offering regeneration, hydration, and glow in a single bottle.
If youโre visiting Korea or exploring K-beauty online,
add a PDRN ampoule to your routine and see how your skin transforms within weeks.
โจ โFrom dull to dewy โ experience the skin-repairing power of PDRN.โ
Want to explore trusted Korean clinics?
Check out YeoTi โ the all-in-one Korean aesthetic app ๐ฐ๐ท๐ฑ
- Over 900,000 verified treatment reviews
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- Consultation and booking available in Japanese and English

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