Plant-based vs. Salmon PDRN Differences: “Are you worried about increasing fine lines and a loss of skin elasticity every time you look in the mirror?” In 2026, PDRN treatments have become a staple for skin regeneration across all ages. However, with the rise of the “Vegan” trend, more people are asking aboutย Plant-based vs. Salmon PDRN differences.
It is natural to feel hesitant about high costs or potential allergic reactions. That is why theย YeoTi Official Blogย has compiled a complete guide on the scientific differences, actual pricing, and expert booking tips to ensure your treatment is a success.

Contents
What Are Plant-based vs. Salmon PDRN Differences?
PDRN (Polydeoxyribonucleotide) consists of short DNA fragments (50~1,500bp) that help regenerate damaged cells and speed up tissue recovery.
1. Salmon-derived PDRN (Animal-based)
- This is extracted from the reproductive cells (sperm) of salmon.
- Because its DNA structure is highly similar to human DNA, it has low rejection rates and promotes rapid tissue healing.
- Known since the 2010s as “Salmon Injections,” it is widely used in treatments like Rejuran Healer to improve elasticity and wrinkles.
2. Plant-based PDRN (Vegan PDRN)
- This is extracted from plant cells such as corn, wheat, and tomatoes, or synthesized through yeast fermentation.
- It completely excludes animal-derived ingredients but maintains a structure and function very similar to traditional PDRN.
- It is ideal for those who prioritize ethical consumption or have sensitive skin, as it can receive vegan certification.

Real Experience & Effect Comparison
Let’s compare the expected changes for those considering treatment:
- Day 1: For salmon PDRN (like Rejuran), you may see temporary bumps (embossing), needle marks, redness, or swelling, which usually subside within a few days.
- Week 1: Skin regeneration is accelerated, and damaged tissues begin to recover.
- Month 1: Collagen synthesis is promoted, leading to visible improvements in elasticity, fine lines, skin texture, and redness.
[Comparison Table: Plant-based vs. Salmon PDRN]
| Category | Salmon PDRN (Animal) | Plant-based PDRN (Vegan) |
| Source | Salmon sperm DNA | Plant cells, Yeast fermentation |
| Main Effects | Powerful regeneration, Improved elasticity | Antioxidant, Calming, Hydration |
| Safety | Proven results; watch for seafood allergies | Lower allergy risk; Vegan certified |
| Recommended For | Those seeking fast, deep regeneration | Sensitive skin, Daily vegan care |
Pricing & Pro Booking Tips
Understanding the Plant-based vs. Salmon PDRN differences is the first step; the next is booking at the right price.
- Salmon PDRN (Rejuran, etc.): Approx.ย 150,000 to 300,000 KRWย per session.
- Plant-based PDRN Care/Ampoules: Approx.ย 50,000 to 100,000 KRWย per session.
“Smart beauty seekers use the YeoTi app to compare local ‘Event Prices’ at a glance.”
Why use YeoTi?
- Transparent Pricing: Check prices including VAT beforehand so there are no surprises at the clinic.
- Easy Mobile Booking: Skip the phone calls and book your appointment instantly through the app.
- Real Reviews: Check unedited before-and-after photos and honest patient feedback.
Side Effects and Precautions
- Salmon PDRN: Rarely, those with seafood or salmon allergies may experience redness or itching, so a consultation is mandatory.
- General: Injection treatments may cause bruising, swelling, pain, or needle marks, which typically improve within 3 to 7 days.
Conclusion
In conclusion, the core of Plant-based vs. Salmon PDRN differences lies in choosing between “Powerful Regeneration” or “Gentle & Ethical Care.” Choose Salmon PDRN for intensive anti-aging, and choose Plant-based PDRN for calming sensitive skin and a vegan lifestyle.
Check YeoTi now for the best “Event Prices” on various skin boosters
FAQ
Q1. How painful is the treatment?ย
A1. While injections may sting, using numbing cream or advanced injectors makes the pain quite manageable.
Q2. How long do the results last?ย
A2. One session typically lasts 1โ2 months. For long-term effects (6+ months), 3 sessions spaced 3โ4 weeks apart are recommended.
Q3. Is Plant-based PDRN less effective?ย
A3. Plant-based is excellent for calming and antioxidants, but Salmon PDRN currently has more clinical evidence for deep-layer skin regeneration.
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